June 22, 2008

What Is Alzheimers Dementia ?

Alzheimers and dementia are not the same thing, but they are very closely related. Most distinction can be observed in the early stages. For instance, in the early stages of Lewy Body Dementia, signs of Alzheimers forgetfulness are not as prevalent as a suddenly diminished attention span, recurrent hallucinations and alarming bouts of lucidity followed by confusion. However, as the dementia progresses, it's almost indistinguishable from Alzheimers Dementia.

Alzheimers Dementia is characterized by increasing and persistent forgetfulness. Alzheimers patients routinely forget names of loved ones, appointments, words to express themselves, or even entire events. Balancing the checkbook or cooking a meal suddenly becomes overwhelming. Emotional mood swings are common, as the Alzheimers patient struggles to deal with confusing emotions and frustration.

Unfortunately, the causes of Alzheimers are not widely understood, although visible brain effects include tau protein tangles and beta-amyloid protein plaques. Inflammation and brain cell death are also triggered in the Alzheimers brain. The average person lives with Alzheimers Dementia for eight years before dying, so it's important than caregivers and patients seek counsel on coping skills.

When most people think of dementia, they're probably thinking about Frontotemporal Dementia, which affects the frontal and temporal lobes of the brain. These dementia patients typically encounter bizarre personality changes, often acting in a socially inappropriate manner. They may be impulsive, emotionally blunted, detached and unable to decipher basic sentences, are unaware of what's going on and are unhygienic. The memory failure commonly associated with Alzheimers Dementia does not affect these patients until the later stages. Roughly 2% of all dementia cases are of this type and most patients live about 10 years from diagnosis. While it is not widely believed that people inherit mental deterioration, this type does appear to run in families, with 20-50% of patients having some sort of history of Frontotemporal Dementia.

 Currently, there is no way to prevent Alzheimers and no cure for Alzheimers Dementia, although researchers are actively looking for ways to halt mental decline at the very least. One research model is a TAU vaccine, which would come in the form of several injections and would stimulate antibody production in the brain, thus preventing deterioration. Other research centers can prevent the amyloid-beta peptide deposits in the brain, which create Alzheimers symptoms. However, researchers suggest they are still 5-10 years from human clinical trials.

Filed under Mental Health by health-updates

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